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Anti -Fas Rabbit pAb

價(jià)格: 在線咨詢(xún)
貨號(hào):
DRF101641
產(chǎn)品規(guī)格:
50 μL
Applications:
Species:
購(gòu)買(mǎi)數(shù)量:
產(chǎn)品詳情 操作說(shuō)明 注意事項(xiàng)

Product Information


Description

Fas rabbit polyclonal

Protein full name

Tumor necrosis factor receptor superfamily member 6

Synonyms

FAS, ALPS1A, APO-1, APT1, CD95, FAS1, FASTM, TNFRSF6, Fas cell surface death receptor

Immunogen

KLH conjugated Synthetic peptide corresponding to human FAS

Isotype IgG
Purity Affinity purification

Predicted MW.

38 kDa

Observed MW.

38 kDa
Uniprot ID

P25445, Q63199, P25446




Applications


Applications

Species

Dilution

Positive Tissue

WB

Human, Mouse, Rat

1:500-1:1000

kidney




Background


Receptor for TNFSF6/FASLG. The adapter molecule FADD recruits caspase-8 to the activated receptor. The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis. FAS-mediated apoptosis may have a role in the induction of peripheral tolerance, in the antigen-stimulated suicide of mature T-cells, or both. The secreted isoforms 2 to 6 block apoptosis (in vitro).




Images



blob.png

All lanes are rat kidney tissue lysate Western blot analysis of FAS (GB13089) at dilution of 1:1000.




Storage



Storage Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles.
Storage Buffer PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol.




NOTE:

1.This product is intended for research only.

2.This product is recommended to dilute with the Primary Antibody Dilution Buffer .

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