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Anti -PDRG1 Rabbit pAb

價(jià)格: 在線咨詢
貨號:
KT012079
產(chǎn)品規(guī)格:
100 μL
Applications:
IHC/IF
Species:
H,M,R
購買數(shù)量:
產(chǎn)品詳情 操作說明 注意事項(xiàng)

Product Information


Description

PDRG1 rabbit polyclonal antibody

Protein full name

p53 and DNA damage-regulated protein 1

Synonyms

Pdrg1, Pdrg, C20orf126, p53 and DNA damage regulated 1

Immunogen

KLH conjugated Synthetic peptide corresponding to Mouse PDRG1

Isotype

IgG

Purity

Affinity purification

Subcellular location

Cytoplasm

Uniprot ID

Q9NUG6, P59048




Applications


Applications

Species

Dilution

Positive Sample

IHC/IF

Human, Mouse, Rat

1: 200-1: 900

esophagus, esophagus cancer, kidney, lung cancer, testis




Background


PDRG1 codes for a novel protein called p53 and DNA damage-regulated protein 1. Human PDRG1 is predominantly expressed in normal testis and its expression can be induced by UV irradiation and be repressed by p53. Recently, PDRG1 was identified as a novel tumor marker for multiple malignancies that is selectively regulated by genotoxic stress. Its expression was upregulated in multiple malignancies including cancers of the colon, rectum, ovary, lung, stomach, breast and uterus when compared to normal tissues, suggesting its being a novel tumor marker that could play a role in cancer development and/or progression.




Images


Immunohistochemistry of paraffin embedded human esophagus using PDRG1 (GB111733) at dilution of 1:300 (200x lens)

Immunohistochemistry of paraffin embedded human lung cancer using PDRG1 (GB111733) at dilution of 1:300 (200x lens)

Immunohistochemistry of paraffin embedded human esophagus cancer using PDRG1 (GB111733) at dilution of 1:300 (300x lens)

Immunohistochemistry of paraffin embedded mouse esophagus using PDRG1 (GB111733) at dilution of 1:300 (200x lens)

Immunohistochemistry of paraffin embedded rat esophagus using PDRG1 (GB111733) at dilution of 1:300 (200x lens)

Immunofluorescence of paraffin embedded human lung cancer using PDRG1 (GB111733) at dilution of 1:300 (200x lens)

Immunofluorescence of paraffin embedded rat testis using PDRG1 (GB111733) at dilution of 1:250 (300x lens)

Immunofluorescence of paraffin embedded mouse kidney using PDRG1 (GB111733) at dilution of 1:250 (200x lens)




Storage


Storage Store at -20 ℃ for one year. Avoid repeated freeze/thaw cycles.
Storage Buffer PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol.


NOTE:

1.This product is intended for research only.

2.This product is recommended to dilute with the Primary Antibody Dilution Buffer (G2025).



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