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Anti -Iba1 Rabbit pAb

價格: 在線咨詢
貨號:
KT011571
產(chǎn)品規(guī)格:
100ul
Applications:
IHC/IF
Species:
H/M/R,H/M/R
購買數(shù)量:
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產(chǎn)品詳情 操作說明 注意事項

Product Information


Description

Iba1 rabbit polyclonal

Protein full name

Allograft inflammatory factor 1

Synonyms

AIF-1, AIF1, G1, IBA1, IRT 1, Protein G1, Ionized calcium-binding adapter molecule 1, MRF1, Microglia response factor, BART 1, AIF1 protein

Immunogen

Recombinant protein corresponding to Mouse Iba1

Isotype

IgG

Purity

Affinity purification

Subcellular location

Cell membraneCytoplasmCytoskeletonCell projection

Uniprot ID

P55008O70200P55009




Applications


Applications

Species

Dilution

Positive Tissue

IHC

Human, Mouse, Rat

1: 500-1: 1000

oligodendroglioma, brain, cerebellum

IF

Human, Mouse, Rat

1: 500-1: 1000

oligodendroglioma, brain, cerebellum




Background


AIF1, also named as G1, IBA1 or daintain/AIF-1, is a 143 amino acid cytoplasmic, inflammation response scaffold protein. It is constitutively expressed in monocytes and macrophages and is known to be involved in macrophage activation. It is a marker of activated macrophage. Despite a lack of detailed knowledge on the in vivo physiological functions of AIF-1, there is growing evidence that shows its aberrant expression contributes to the pathogenesis of many autoimmune diseases, including rheumatoid arthritis.  AIF1 is an actin-binding protein that enhances membrane ruffling and RAC activation. It enhances lymphocyte migration and the actin-bundling activity of LCP1. 




Images


Immunohistochemistry analysis of paraffin-embedded human oligodendroglioma using iba1 (GB113502) at dilution of 1: 1000

Immunohistochemistry analysis of paraffin-embedded mouse brain using 

iba1 (GB113502) at dilution of 1: 1000

Immunohistochemistry analysis of paraffin-embedded rat brain using 

iba1 (GB113502) at dilution of 1: 1000

Immunohistochemistry analysis of paraffin-embedded rat cerebellum using 

iba1 (GB113502) at dilution of 1: 1000

Immunofluorescent analysis of paraformaldehyde-fixed human oligodendroglioma using iba1 (GB113502) at dilution of 1: 1000

Immunofluorescent analysis of paraformaldehyde-fixed mouse brain using 

iba1 (GB113502) at dilution of 1: 1000

Immunofluorescent analysis of paraformaldehyde-fixed rat brain using 

iba1 (GB113502) at dilution of 1: 1000

Immunofluorescent analysis of paraformaldehyde-fixed mouse cerebellum using iba1 (GB113502) at dilution of 1: 1000

Immunofluorescent analysis of paraformaldehyde-fixed rat cerebellum using iba1 (GB113502) at dilution of 1: 1000




Storage


Storage Store at -20 ℃ for one year. Avoid repeated freeze/thaw cycles.
Storage Buffer PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol.


NOTE:

1.This product is intended for research only.

2.This product is recommended to dilute with the Primary Antibody Dilution Buffer .

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