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Anti -OB Cadherin Rabbit pAb

價格: 在線咨詢
貨號:
KT011882
產(chǎn)品規(guī)格:
100 μL
Applications:
WB
Species:
HMR
購買數(shù)量:
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產(chǎn)品詳情 操作說明 注意事項

Product Information


Description

OB Cadherin rabbit polyclonal antibody

Protein full name

Cadherin-11

Synonyms

OSF-4, Osteoblast cadherin, OB-cadherin, Cdh11, CAD11, Cadherin 11 type 2

Immunogen

KLH conjugated Synthetic peptide corresponding to Mouse OB Cadherin

Isotype

IgG

Purity

Affinity purification

Predicted MW.

88 kDa

Observed MW.

120 kDa

Uniprot ID

P55287, P55288, F1MAH6




Applications


Applications

Species

Dilution

Positive Tissue

WB

Human, Mouse, Rat

1: 500-1: 1000

brain, lung, testis




Background


The cadherin super family comprises a large number of membrane glycoproteins with one or more cadherin repeats, which are involved in Ca2+ dependent cell-cell adhesion. Cadherin-11, also known as OB-cadherin, is a type II classical cadherin. Classical cadherins are type I transmembrane proteins with an N-terminal extracellular domain containing five tandem cadherin repeats and a C-terminal cytoplasmic domain with a characteristic sequence for binding to catenins. Type I cadherins differ from type II cadherins by the presence of the HAV tripeptide motif in the most N-terminal cadherin repeat. Classic cadherins mediate cell-cell adhesion preferentially via homotypic interactions and form adherens juctions that have beta -catenin and p120 (ctn) at the cytoplasmic side of the junction. Homotypic cadherin interactions also transduce outside-in and inside-out cell signals.




Images


Picture 1.png

Western blot analysis of OB-Cadherin (GB111008) at dilution of 1: 500




Storage


Storage Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles.
Storage Buffer PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol.




NOTE:

1.This product is intended for research only.

2.This product is recommended to dilute with the Primary Antibody Dilution Buffer .


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