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Anti -Lipocalin-2 / NGAL Rabbit pAb
價格：
在線咨詢
貨號：
KT011984
產(chǎn)品規(guī)格：
100ul
Applications：
IHC/IF
Species：
H
購買數(shù)量：
產(chǎn)品詳情
操作說明
注意事項
Product Information
|
Description |
NGAL rabbit polyclonal antibody |
|
Protein full name |
Neutrophil gelatinase-associated lipocalin |
|
Synonyms |
NGAL, Lipocalin-2, Oncogene 24p3, Siderocalin, p25 |
|
Immunogen |
Recombinant protein corresponding to Human NGAL |
|
Isotype |
IgG |
|
Purity |
Affinity purification |
|
Subcellular location |
Secreted |
|
Uniprot ID |
P80188 |
Applications
|
Applications |
Species |
Dilution |
Positive Sample |
|
IHC/IF |
Human |
1: 500-1: 3000 |
colon, liver, liver cancer, lung, lung cancer |
Background
Lipocalin 2 is a member of the lipocalin family, It involved in multiple processes such as apoptosis, innate immunity and renal development. Binds iron through association with 2,5-dihydroxybenzoic acid (2,5- DHBA), a siderophore that shares structural similarities with bacterial enterobactin, and delivers or removes iron from the cell, depending on the context. Involved in apoptosis due to interleukin-3 (IL3) deprivation: iron-loaded form increases intracellular iron concentration without promoting apoptosis, while iron-free form decreases intracellular iron levels, inducing expression of the proapoptotic protein BCL2L11/BIM, resulting in apoptosis.
Images
|
|
Immunohistochemistry of paraffin embedded human liver using NGAL (GB111134) at dilution of 1:1000 (400x lens) |
|
|
Immunohistochemistry of paraffin embedded human liver cancer using NGAL (GB111134) at dilution of 1:1000 (400x lens) |
|
|
Immunohistochemistry of paraffin embedded human lung using NGAL (GB111134) at dilution of 1:1000 (400x lens) |
|
|
Immunohistochemistry of paraffin embedded human lung cancer using NGAL (GB111134) at dilution of 1:1000 (400x lens) |
|
|
Immunofluorescence of paraffin embedded human colon using NGAL (GB111134) at dilution of 1:2000 (400x lens) |
Storage
| Storage | Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles. |
| Storage Buffer | PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol. |
NOTE:
1.This product is intended for research only.
2.This product is recommended to dilute with the Primary Antibody Dilution Buffer .
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合肥萬物生物科技有限公司
客服熱線：400-1016-218
QQ：355185756
地址：安徽省合肥市高新區(qū)黃山路602號合肥國家大學科技園A401室