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Anti -WDFY3 Rabbit pAb

價(jià)格: 在線咨詢
貨號:
KT012176
產(chǎn)品規(guī)格:
100 μL
Applications:
IHC/IF
Species:
H
購買數(shù)量:
產(chǎn)品詳情 操作說明 注意事項(xiàng)

Product Information


Description

WDFY3 rabbit polyclonal antibody

Protein full name

WD repeat and FYVE domain-containing protein 3

Synonyms

ALFY, Autophagy linked FYVE protein, KIAA0993, WDFY3, ZFYVE25, BWF1

Immunogen

KLH conjugated Synthetic peptide corresponding to Mouse WDFY3

Isotype

IgG

Purity

Affinity purification

Subcellular location

Cytoplasm, Membrane, Nucleus

Uniprot ID

Q8IZQ1




Applications


Applications

Species

Dilution

Positive Sample

IHC/IF

Human

1: 400-1: 1300

colon, colon cancer




Background


WDFY3 also called ALFY, is a phosphatidylinositol 3-phosphate-binding protein that functions as a master conductor for aggregate clearance by autophagy.This protein shuttles from the nuclear membrane to colocalize with aggregated proteins, where it complexes with other autophagic components to achieve macroautophagy-mediated clearance of these aggregated proteins. However, it is not necessary for starvation-induced macroautophagy.




Images


Picture 1.png Immunohistochemistry of paraffin embedded human colon using WDFY3 (GB111969) at dilution of 1:700 (400x lens)

Picture 2.png

Immunohistochemistry of paraffin embedded human colon cancer using WDFY3 (GB111969) at dilution of 1:700 (400x lens)




Storage


Storage Store at -20 ℃ for one year. Avoid repeated freeze/thaw cycles.
Storage Buffer PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol.


NOTE:

1.This product is intended for research only.

2.This product is recommended to dilute with the Primary Antibody Dilution Buffer (G2025).


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